Similarity of Ribosomal and Ribosomal Precursor RNA's from Rat Liver and the Novikoff Ascites Hepatoma1

rat liver and the Novikoff hepatoma have been examined by two competitive hybridization techniques and by nucleotide analyses. Significant differences were not found between the corresponding RNA of these tissues by competition of labeled RNA from the hepatoma with unlabeled 18 and 28 S ribosomal RNA and 28 and 45 S nucleolar RNA of liver and hepatoma by sequential or simultaneous competition hybridization. Differences were found in the specific activity of 32P-labeled nucleotides, but no significant differences